67-year-old male presenting to the clinic with complaints of dry mouth mostly at night, which he says causes him to urinate a lot during the day and at night. Drinking water helps his problems during the daytime.

Past medical history is HTN, hyperlipidemia, pre diabetic, urinary incontinence, enlarged prostate, BMI > 30, ED, UTI, HSV1, And obesity. Metformin 1000 mg POQ day, amlodipine 10 mg POQ day, Clonidine 0.1 mg PO BID, Tamsulosin 0.4 mg POQ day, lisinopril 40 mg POQ day, atorvastatin 40 mg POQ day. Pt has drank out of the sink 2 times during the interview.

1. What is your diagnosis?

2. What labs or procedures are you running to confirm your diagnosis?

3. What are the potential causes of polyuria?

4. List at least four labs that would indicate dehydration?

5. What labs would indicate that polydipsia/polyuria was due to hyperglycemia?

6. What guideline could you use to determine the best treatment for this patient?

Question 1 of 6


American Diabetes Association. (2021). Classification and Diagnosis of Diabetes: Standards
of Medical Care in Diabetes, Diabetes Care 1 January 2021; 44 (Supplement_1): S15–S33.

Maddaloni, E, Bolli, GB, Frier, BM, et al. C-peptide determination in the diagnosis of type of
diabetes and its management: A clinical perspective. Diabetes Obes Metab. 2022; 24( 10):
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